Dichlorvos and lindane induced oxidative stress in rat brain: Protective effects of ginger.
Pharmacognosy Res. 2012 Jan; 4(1): 27-32
Sharma P, Singh R
Dichlorvos and lindane pesticide causes toxicity in animals including humans. Ginger (Zingiber officinale) is widely used as a culinary medicine in the Ayurvedic system of medicine, possessing a number of pharmacological properties.This study was designed to assess ameliorating effects of ginger juice in dichlorvos and lindane induced neurotoxicity in wistar rats.Dichlorvos (8.8 mg/kg bw) and lindane (8.8 mg/kg bw) were orally administered alone as well as in combination to adult male and female wistar rats for 14 days followed by the post-treatment of ginger juice (100 mg/kg bw) for 14 days. Lipid peroxidation (LPO), reduced glutathione (GSH), and activities of antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione S-transferase (GST), glutathione reductase (GR), quinine reductase (QR), and protein level were measured to evaluate the toxicity of these pesticides in brain.Dichlorvos and lindane administration alone and in combination increased LPO and decreased the GSH level, SOD, CAT, GPx, GST, GR, QR activity, and protein. Oxidative stress due to abnormal production of reactive oxygen species (ROS) is believed to be involved in the toxicities induced by these pesticides. Post-treatment of ginger juice decreased LPO and increased the level of GSH, SOD, CAT, GPx, GST, GR, QR activity and protein in the brain of rats.The results indicated that dichlorovos and lindane induced tissue damage was ameliorated by ginger juice.
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This week's Culinary SOS: Veggie burgers from North Peak Brewing Co.
This week's Culinary SOS comes to us from Stephanie Schultz in Playa del Rey: My family and I just got back from a trip to Traverse City, Mich., where I had the absolute best veggie burger I've ever had. Is…
Sat, 14 Jan 2012 08:07:34 -0800
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Open Question: Needing some adivce about relationships in college?
Sorry it’s kind of long.
I’m a Senior in High School which happens to be the only High School in this small town. Over the course of these past two years i have been coming to terms with my sexuality. I’m an average girl who happens to be a lesbian, which in this small baptist town is frowned upon. Its no secret though that i like girls to most people in this town (go figure), but there are many girls that swing my way, if you should say, but are afraid of being judged.
I had one GF in October of 2010 who didn’t want our relationship to be known to most/certain people. We grew close, then she left me for, basicly, a hill billy, she got pregnant and lost the baby becuz of drugs…After her i’ve only had one other GF, which was in November of last year…
My problem is this, since i can’t find someone here, should i wait until college or should i try to put myself out there, with say the help of a dating website (i am soon to be 18)?
Is there any hope of me finding a GF in the near future? (My focus on school is sharp and i am planning on a career in psychology and culinary after college.) Advice or anything useful would be greatly appreciated, thank you 
Fri, 13 Jan 2012 05:10:03 GMT
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Central Holidays Introduces Paris Vacation Packages for Valentine’s Day Getaways
New value-added programs offer expanded romantic inclusions for Paris vacations during Valentines Day.
(PRWeb January 10, 2012)
Read the full story at
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Local chefs share their culinary skills with kids and adults …
Laura Content, a professional pastry chef, and Allen Doty, head chef at Riccardos Ristorante in Lake Oswego, will conduct hands-on classes for all ages.
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